SOE ’95 - Xth CONGRESS EUROPEAN of the
SOCIETY OF OPHTHALMOLOGY
MILANO, JUNE 25-29. 1995
COMBINATION EYE DROPS VERSUS DICLOFENAC EYE DROPS AFTER CATARACT SURGERY
N Ray-Chaudhuri1, N Suong1, IK
Jalili2, M IqbaI2, M Iqbal2,
TT Shetty3, P Phelan 4, P Sunderraj5.
Royal Victoria Infirmary
Newcastle, UK; 2 District General Hospital, Warrington, UK;
3 Cumberland Infirmary, Carlisle, UK; 4 Eye
Infirmary, Sunderland, UK; 5 CIBA Vision Ophthalmics, Bülach,
evaluate the efficacy and safety of Diclofenac-Genamicin combination eye
drops in comparison with Diclofenac eye drops in the treatment of ocular
inflammation following extracapsular cataract surgery and lens
randomized, observer-masked, parallel-group, four-week, seven-centre
evaluation of 295 patients (Diclofenac-Gentamicin 146, Diclofenac 149).
two treatment groups were similar at baseline. There was no difference
between the two study groups in the sum of the grades of anterior chamber
flare and cells on post-operative day 5-8 (p = 0.9) and day 12-16 (p =
0.8). Although corneal epithelial staining was higher on
Diclofenac-Gentamicin compared with Diclofenac, there was no difference in
subjective local tolerance between the two medications.
addition of Gentanicin did not interfere with the demonstrated
anti-inflammatory efficacy of diclofenac eye drops in controlling
post-cataract surgery intraocular inflammation.